Poisoning Prevention, Treatment, and Detection as Public Health Investments

Assessing the Economic and Societal Value of the U.S. Poison Center Network

David Metz, Elizabeth Marsolais, Anthony Yu, Elena Younossi, Benjamin M. Miller, Chandra Garber

ResearchPublished Jan 21, 2026

Cover: Poisoning Prevention, Treatment, and Detection as Public Health Investments

The U.S. Poison Center Network provides a wide variety of services to the public, government entities, health care providers and institutions, product manufacturers, and public health organizations and researchers. The Poison Center Network in the United States is composed of regional Poison Centers and their national accrediting organization, America's Poison Centers®. To assess the economic and societal value of the Poison Center Network, the authors conducted a survey of individual Poison Centers to collect information on the scope and scale of services provided, operational costs, and sources of funding, as well as individual and group interviews with stakeholders.

To describe and estimate the monetary value of the benefits provided by Poison Centers, the authors developed a logic model framework, mapping Poison Center inputs (i.e., resources and staff) to activities (i.e., essential and ancillary functions), outcomes, and impacts. The authors then used a benefit-cost analysis framework to estimate a return on investment — the tangible and intangible returns, to the extent feasible, to society for every dollar spent by Poison Centers to help prevent, treat, and manage poisonings and exposures. Overall, the Poison Centers provide significant returns to society for every dollar spent, including cost savings because of avoidable medical utilization, reduced patient length of stay, mortality risk reduction, and enhanced national public health surveillance.

Key Findings

  • The Poison Center Network yields benefits totaling approximately $3.1 billion each year.
  • Every $1 spent by Poison Centers on services generates $16.77 in benefits.
  • The Poison Center Network has taken on an expanded public health role, particularly in toxicosurveillance and emergency preparedness and response.
  • Many Poison Centers are providing ancillary services on top of their essential (i.e., toxicological) functions.
  • Human exposure cases have declined only slightly, and overall case intensity has increased.
  • The ways stakeholders can interact with the Poison Centers are changing, with some Poison Centers offering text message and chat options for engagement in addition to telephone calls.
  • The total number of Poison Center encounters has decreased since the early 2010s because of a large decline in information requests, possibly driven by the proliferation of alternative online information sources.
  • Funding for Poison Centers' essential functions has decreased in real dollar terms. Congressionally appropriated funding and some state funding sources have declined in real dollar terms because funding amounts have not been adjusted for inflation in more than a decade.
  • In-kind support from a host institution or other affiliate — usually a hospital or university providing facilities, utilities, information technology, human resources functions, or salaries — has also decreased.
  • The expansion of Poison Centers' ancillary functions may be a response to financial pressures because of the rising costs of providing services to ensure that operational needs are met.

Topics

Document Details

  • Publisher: RAND Corporation
  • Availability: Web-Only
  • Year: 2026
  • Pages: 80
  • DOI: https://doi.org/10.7249/RRA3829-1
  • Document Number: RR-A3829-1

Citation

Chicago Manual of Style

Metz, David, Elizabeth Marsolais, Anthony Yu, Elena Younossi, Benjamin M. Miller, and Chandra Garber, Poisoning Prevention, Treatment, and Detection as Public Health Investments: Assessing the Economic and Societal Value of the U.S. Poison Center Network. Santa Monica, CA: RAND Corporation, 2026. https://www.rand.org/pubs/research_reports/RRA3829-1.html.
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