Fentanyl and Other Synthetic Opioids

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Press

Sep 29, 2025

Medicaid Unwinding Associated with Less Medication Treatment for Opioid Use Disorder

The end of pandemic-era enrollment enhancements for Medicaid was associated with a rise in the number of people ending medication treatment for opioid use disorder, as well as a decrease in the number of people beginning such treatment.
Research

Sep 22, 2025

Geography And Fentanyl: Explaining The Disproportionate Rise In Opioid Overdose Deaths Among Black Americans

The article analyzes how geography and structural factors have driven a disproportionate rise in fentanyl overdose deaths among Black Americans, highlighting shifts in drug markets and the need to tailor interventions to changing risks.
Research

Sep 4, 2025

Estimates of Illicit Opioid Use in the US

The objective of this paper is to estimate the prevalence of illicit opioid use, including illicitly manufactured fentanyl, and initial opioid exposure among those reporting illicit opioid use.
Event

Aug 28, 2025

The Future of Fentanyl and Other Synthetic Opioids

Since 2013, illegally manufactured fentanyl has been linked to approximately 450,000 drug overdose deaths in the United States. These deaths appear to be declining, but new threats are emerging.. What actions might be taken to confront this evolving crisis?
Research

Aug 27, 2025

Historical and Contextual Variation in Daily Opioid Consumption Rates: Implications for Supply Control, Service Delivery, and Research

The objective of this paper is to examine how consumption varies across time and context, with implications for treatment and drug policy.
Research

Aug 27, 2025

Cross-sectional Examination of Characteristics of Higher-Dose Buprenorphine Prescriptions During the Era of Illicit Fentanyl

To better understand buprenorphine prescribing patterns, this manuscript examines the frequency and characteristics of dispensed buprenorphine of ≤ 16mg, > 16-24 mg, and > 24 mg daily dose.
Podcast

May 30, 2025

Duration 29:20

Stopping the Flow of Fentanyl

What might it take to curb the supply of fentanyl and other synthetic opioids in the United States? RAND's David Luckey says a "whole-of-nation" approach is needed.
Tool

Apr 22, 2025

Substance Use Treatment and Recovery Team Addiction Consultation Service (START ACS): An Addiction Consultation Service for Opioid Use Disorder

This guide describes the Substance Use Treatment and Recovery Team Addiction Consultation Service, a program that aims to enhance treatment initiation and ensure successful connections to follow-up care for people with opioid use disorder.
Commentary

Mar 13, 2025

Reducing Deaths from Fentanyl and Other Illicit Opioids: Q&A with David Luckey

In 2022, a bipartisan commission on combating synthetic opioid trafficking released its final report, a point-by-point strategy to address the opioid crisis and reduce its death toll. RAND's David Luckey discusses the report and what still needs to be done to combat the crisis.
Tool

Mar 13, 2025

OPTIC R Repository and Tutorial for Creating Policy Wheel Data Visualizations

This R-based tool (and accompanying tutorial) allows users to create Opioid Policy Tools and Information Center (OPTIC)-style policy wheel data visualizations that illustrate the timeline over which state policies are implemented.
Research

Jan 23, 2025

Polydrug Use Among Patients on Methadone Medication Treatment: Evidence from Urine Drug Testing to Inform Patient Safety

This study measured trends in illicit substance use from 2017 to 2021 in a large multi-state population of patients in methadone medication treatment for opioid use disorder (M-MOUD) and persistence of substance use in the first year of treatment.
Research

Nov 27, 2024

Rates of Receiving Medication for Opioid Use Disorder and Opioid Overdose Deaths During the Early Synthetic Opioid Crisis: A County-Level Analysis

We used a spatio-temporal modeling approach to determine that higher rates of receiving medications for opioid use disorder in 2012-2014 was associated with lower rates of synthetic opioid overdose deaths early in the crisis.

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Fentanyl and Other Synthetic Opioids

Fentanyl and Other Synthetic Opioids

Related Topics

Stopping the Flow of Fentanyl

Countering Fentanyl with Diplomacy

Explore RAND’s Work on this Topic

Error

Medicaid Unwinding Associated with Less Medication Treatment for Opioid Use Disorder

Geography And Fentanyl: Explaining The Disproportionate Rise In Opioid Overdose Deaths Among Black Americans

Estimates of Illicit Opioid Use in the US

The Future of Fentanyl and Other Synthetic Opioids

Historical and Contextual Variation in Daily Opioid Consumption Rates: Implications for Supply Control, Service Delivery, and Research

Cross-sectional Examination of Characteristics of Higher-Dose Buprenorphine Prescriptions During the Era of Illicit Fentanyl

Stopping the Flow of Fentanyl

Substance Use Treatment and Recovery Team Addiction Consultation Service (START ACS): An Addiction Consultation Service for Opioid Use Disorder

Reducing Deaths from Fentanyl and Other Illicit Opioids: Q&A with David Luckey

OPTIC R Repository and Tutorial for Creating Policy Wheel Data Visualizations

Polydrug Use Among Patients on Methadone Medication Treatment: Evidence from Urine Drug Testing to Inform Patient Safety

Rates of Receiving Medication for Opioid Use Disorder and Opioid Overdose Deaths During the Early Synthetic Opioid Crisis: A County-Level Analysis

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Fentanyl and Other Synthetic Opioids

Fentanyl and Other Synthetic Opioids

Related Topics

Stopping the Flow of Fentanyl

Countering Fentanyl with Diplomacy

Explore RAND’s Work on this Topic

Error

Medicaid Unwinding Associated with Less Medication Treatment for Opioid Use Disorder

Geography And Fentanyl: Explaining The Disproportionate Rise In Opioid Overdose Deaths Among Black Americans

Estimates of Illicit Opioid Use in the US

The Future of Fentanyl and Other Synthetic Opioids

Historical and Contextual Variation in Daily Opioid Consumption Rates: Implications for Supply Control, Service Delivery, and Research

Cross-sectional Examination of Characteristics of Higher-Dose Buprenorphine Prescriptions During the Era of Illicit Fentanyl

Stopping the Flow of Fentanyl

Substance Use Treatment and Recovery Team Addiction Consultation Service (START ACS): An Addiction Consultation Service for Opioid Use Disorder

Reducing Deaths from Fentanyl and Other Illicit Opioids: Q&A with David Luckey

OPTIC R Repository and Tutorial for Creating Policy Wheel Data Visualizations

Polydrug Use Among Patients on Methadone Medication Treatment: Evidence from Urine Drug Testing to Inform Patient Safety

Rates of Receiving Medication for Opioid Use Disorder and Opioid Overdose Deaths During the Early Synthetic Opioid Crisis: A County-Level Analysis

Oops! An unexpected error has occurred.