Osteoarthritis

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Research

Feb 2, 2026

Referral Pathways Into the NHS Digital Weight Management Programme for Musculoskeletal and Perioperative Patients: Rapid Process Evaluation

To understand reasons for variation and experiences of the implementation and functioning of referral pathways for musculoskeletal and elective surgical care patients into the NHS Digital Weight Management Programme.
Research

Apr 17, 2024

Evaluation of Dynamic Effects of Depressive Symptoms on Physical Function in Knee Osteoarthritis

In this paper, we assess how changes in depressive symptoms influence physical function over time among those with radiographic knee osteoarthritis.
Research

Apr 17, 2024

Time-varying Treatment Effect Modification of Oral Analgesic Effectiveness by Depressive Symptoms in Knee Osteoarthritis: An Application of Structural Nested Mean Models in a Prospective Cohort

Depressive symptoms are common in knee osteoarthritis, and may exacerbate pain severity or impact efficacy of analgesics. The aim was to assess whether oral analgesic effectiveness in knee osteoarthritis varies by fluctuations in depressive symptoms.
Research

Jun 25, 2020

Association Between Disease Progression and Depression Onset in Persons with Radiographic Knee Osteoarthritis

In summary, study findings indicate that greater structural disease severity and decreased physical performance increase the risk of depression onset among individuals with radiographic knee osteoarthritis.
Research

Jun 14, 2019

Depression Subtypes in Persons with or at Risk for Symptomatic Knee Osteoarthritis

Among persons with or at-risk for symptomatic knee OA, there is evidence of depression subtypes characterized by distinct clusters of depressive symptoms that have differential effects on reports of pain and disability overtime.
Research

Feb 7, 2019

Pain Severity as a Mediator of the Association Between Depressive Symptoms and Physical Performance in Knee Osteoarthritis

This study examined whether pain severity mediates the association between depressive symptoms and physical performance in persons with radiographic knee osteoarthritis.
Project

Jan 26, 2018

The Economic Returns of Musculoskeletal Research

Researchers estimated the health and economic benefits of UK investment in medical research into musculoskeletal disease (MSD). Their best estimate of the internal rate of return from MSD-related research was 7%, which is similar to the 9% for cardiovascular disease and 10% for cancer research.
Research

Sep 5, 2017

Economic Value of Advanced Transfemoral Prosthetics

RAND researchers developed a simulation model to assess the clinical outcomes and costs of microprocessor-controlled knees compared with more-traditional non-microprocessor-controlled knees.
Research

Sep 5, 2017

القيمة الاقتصادية للأطراف الاصطناعية المزودة بركبة

طور باحثو مؤسسة RAND نموذج محاكاة لتقييم الفروقات في النتائج السريرية والكلفة بين الركب الاصطناعية العاملة بمشغّل دقيق وتلك غير العاملة بمشغّل دقيق.
Research

Nov 28, 2016

Hyaluronic Acid Injection Therapy for Osteoarthritis of the Knee: Concordant Efficacy and Conflicting Serious Adverse Events in Two Systematic Reviews

A lack of standards for reporting and synthesizing adverse events associated with common treatments can lead to conflicting conclusions about the balance of their benefits and harms.
Research

Jan 25, 2016

Development of System-Level Performance Measures for Evaluation of Models of Care for Inflammatory Arthritis in Canada

This study aims to develop system-level performance measures for evaluating the care of patients with inflammatory arthritis (IA), including rheumatoid arthritis (RA), psoriatic arthritis, ankylosing spondylitis, and juvenile idiopathic arthritis.
Commentary

Jan 22, 2016

More Research Is Needed on Artificial Joints and Patients Can Play a Key Role

Safety problems with artificial knees and hips, including product recalls, highlight the need for more patient-centered research. RAND has partnered with CreakyJoints in a project intended to train a group of patients to get involved in research on this topic.

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Osteoarthritis

Osteoarthritis

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Explore RAND’s Work on this Topic

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Referral Pathways Into the NHS Digital Weight Management Programme for Musculoskeletal and Perioperative Patients: Rapid Process Evaluation

Evaluation of Dynamic Effects of Depressive Symptoms on Physical Function in Knee Osteoarthritis

Time-varying Treatment Effect Modification of Oral Analgesic Effectiveness by Depressive Symptoms in Knee Osteoarthritis: An Application of Structural Nested Mean Models in a Prospective Cohort

Association Between Disease Progression and Depression Onset in Persons with Radiographic Knee Osteoarthritis

Depression Subtypes in Persons with or at Risk for Symptomatic Knee Osteoarthritis

Pain Severity as a Mediator of the Association Between Depressive Symptoms and Physical Performance in Knee Osteoarthritis

The Economic Returns of Musculoskeletal Research

Economic Value of Advanced Transfemoral Prosthetics

القيمة الاقتصادية للأطراف الاصطناعية المزودة بركبة

Hyaluronic Acid Injection Therapy for Osteoarthritis of the Knee: Concordant Efficacy and Conflicting Serious Adverse Events in Two Systematic Reviews

Development of System-Level Performance Measures for Evaluation of Models of Care for Inflammatory Arthritis in Canada

More Research Is Needed on Artificial Joints and Patients Can Play a Key Role

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Osteoarthritis

Osteoarthritis

Related Topics

Explore RAND’s Work on this Topic

Error

Referral Pathways Into the NHS Digital Weight Management Programme for Musculoskeletal and Perioperative Patients: Rapid Process Evaluation

Evaluation of Dynamic Effects of Depressive Symptoms on Physical Function in Knee Osteoarthritis

Time-varying Treatment Effect Modification of Oral Analgesic Effectiveness by Depressive Symptoms in Knee Osteoarthritis: An Application of Structural Nested Mean Models in a Prospective Cohort

Association Between Disease Progression and Depression Onset in Persons with Radiographic Knee Osteoarthritis

Depression Subtypes in Persons with or at Risk for Symptomatic Knee Osteoarthritis

Pain Severity as a Mediator of the Association Between Depressive Symptoms and Physical Performance in Knee Osteoarthritis

The Economic Returns of Musculoskeletal Research

Economic Value of Advanced Transfemoral Prosthetics

القيمة الاقتصادية للأطراف الاصطناعية المزودة بركبة

Hyaluronic Acid Injection Therapy for Osteoarthritis of the Knee: Concordant Efficacy and Conflicting Serious Adverse Events in Two Systematic Reviews

Development of System-Level Performance Measures for Evaluation of Models of Care for Inflammatory Arthritis in Canada

More Research Is Needed on Artificial Joints and Patients Can Play a Key Role

Oops! An unexpected error has occurred.