Toward an Asthma Patient-Reported Outcome Measure for Use in Digital Remote Monitoring

Robert S. Rudin, Nabeel Qureshi, Dinah Foer, Anuj K. Dalal, Maria Orlando Edelen

ResearchPosted on rand.org Sep 22, 2021Published in: Journal of Asthma (2021). doi: 10.1080/02770903.2021.1955378

Objective

To develop and test a patient-reported outcome measure (PROM) for suitability in digital remote asthma symptom monitoring to identify uncontrolled asthma.

Methods

We modified a 5-item PROM that does not require a license, the asthma control measure (ACM), from a one-month to one-week lookback period, and evaluated it using the 5-item asthma control questionnaire (ACQ-5). We recruited subjects with asthma through MTurk, an online platform.

Results

In a sample of 498 subjects, the ACM identified uncontrolled asthma with sensitivity 0.99 and specificity 0.65. The two measures correlated with r = 0.81.

Conclusion

The ACM modified to a weekly lookback period can differentiate patients with well-controlled asthma from those with uncontrolled asthma. This PROM does not require a license and can be used in digital remote monitoring interventions.

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Document Details

  • Copyright: RAND Corporation
  • Publisher: Taylor & Francis Group, LLC
  • Availability: Non-RAND
  • Year: 2021
  • Pages: 6
  • Document Number: EP-68724

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