Biology and Life Sciences

373 Results

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Research

Dec 12, 2025

Ethical Criteria for Self-Identifying Societal Risk Associated with Dangerous Gain-of-Function Research

We suggest a layered review process for the assessment of societal consequences to inform implementation of the 5 May 2025 executive order "Improving the safety and security of biological research."
Commentary

Dec 11, 2025

A Roadmap for Accelerating Therapies for Parkinson's Disease

The discovery of a gene pathway that contributes to Parkinson's risk has opened up a promising new avenue for developing therapies. Delivering a therapy that slows or prevents Parkinson's progression will require intentional and sustained collaboration across stakeholders.
Expert Insights

Dec 10, 2025

Advancing Development of LRRK2-Targeted Therapeutics for Parkinson’s Disease: Conference Proceedings and Roadmap for Research

The authors highlight topics discussed in a June 2025 workshop hosted by The Michael J. Fox Foundation for Parkinson’s Research about the development of therapeutics that target the leucine-rich repeat kinase 2 pathway to treat Parkinson’s disease.
Research

Dec 1, 2025

Mapping the Informal Bioeconomy: Assessing the Current Landscape and Opportunities for Reinforcing Biosafety and Biosecurity

The rapid growth of biotechnology research has resulted in a powerful ecosystem known as the bioeconomy. In this report, the authors seek to map and evaluate the informal bioeconomy from a biosecurity perspective.
Research

Nov 25, 2025

Toward Comprehensive Benchmarking of the Biological Knowledge of Frontier Large Language Models

The authors evaluate the most-capable artificial intelligence (AI) models (as of May 2025) against eight knowledge benchmarks to determine the degree to which frontier AI models pose a risk of helping bad actors create biological or chemical weapons.
Research Summary

Nov 18, 2025

Legitimate Research or Biological Threat? Detecting Misuse of the Biological Supply Network and Policy Options to Reduce Risks

This research brief highlights the critical points and mitigation strategies that RAND researchers made in their report about how bad actors could exploit the biological supply network to develop biological weapons.
Research

Nov 10, 2025

A Review of U.S. Military Traumatic Brain Injury Studies: Trends, Gaps, and Opportunities

In this scoping review of military service–related traumatic brain injury (TBI) studies, authors map TBI research from 2015 to 2025 and identify overlaps and gaps to inform opportunities to better align research efforts and investments.
Research

Oct 31, 2025

Experiential Learning from Rapid Evaluation in Health and Care

We argue that rapid evaluation provides essential evidence into time-sensitive decision-making by planners and policymakers, while requiring an approach that can help balance the inherent trade-off between rapidity and rigour.
Research

Oct 30, 2025

"Who Are You Going to Call?": Research Ethics Consultation Directors' Perspectives on Barriers and Facilitators

This study aimed to identify key barriers and facilitators affecting the success of research ethics consultation services, particularly in light of changes in funding and institutional support.
Commentary

Oct 28, 2025

Defining Risk in Biological Research: Why Researchers Need Clearer Oversight Frameworks

As the U.S. government continues to consider the future for dangerous gain-of-function policies, ongoing research and refining objective and reproducible assessment tools can strike the right balance: preventing misuse while still supporting the science that drives innovations in medicine and biotechnology.
Research

Oct 20, 2025

Protecting Biological Materials and Services from Misuse: Opportunities for Access Monitoring and Control

The authors explore critical points within the biological supply network that bad actors might exploit to develop biological weapons. The authors develop recommendations for enhancing data collection, regulatory oversight, and threat mitigation.
Research Summary

Oct 1, 2025

When Should We Worry About AI Being Used to Design a Pathogen? Biology and AI Experts Weigh In

Concerns that artificial intelligence (AI) might enable pathogen design are increasing, but risks and timelines remain unclear. This brief describes a Delphi study of biology and AI experts who debated potential limits to AI-enabled pathogen design.

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Biology and Life Sciences

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Related Topics

Dissecting America's AI Action Plan: A Primer for Biosecurity Researchers

Silent Speech, Loud Questions: The Dawn of Brain-Computer Communication

Explore RAND’s Work on this Topic

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Ethical Criteria for Self-Identifying Societal Risk Associated with Dangerous Gain-of-Function Research

A Roadmap for Accelerating Therapies for Parkinson's Disease

Advancing Development of LRRK2-Targeted Therapeutics for Parkinson’s Disease: Conference Proceedings and Roadmap for Research

Mapping the Informal Bioeconomy: Assessing the Current Landscape and Opportunities for Reinforcing Biosafety and Biosecurity

Toward Comprehensive Benchmarking of the Biological Knowledge of Frontier Large Language Models

Legitimate Research or Biological Threat? Detecting Misuse of the Biological Supply Network and Policy Options to Reduce Risks

A Review of U.S. Military Traumatic Brain Injury Studies: Trends, Gaps, and Opportunities

Experiential Learning from Rapid Evaluation in Health and Care

"Who Are You Going to Call?": Research Ethics Consultation Directors' Perspectives on Barriers and Facilitators

Defining Risk in Biological Research: Why Researchers Need Clearer Oversight Frameworks

Protecting Biological Materials and Services from Misuse: Opportunities for Access Monitoring and Control

When Should We Worry About AI Being Used to Design a Pathogen? Biology and AI Experts Weigh In

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Biology and Life Sciences

Biology and Life Sciences

Related Topics

Dissecting America's AI Action Plan: A Primer for Biosecurity Researchers

Silent Speech, Loud Questions: The Dawn of Brain-Computer Communication

Explore RAND’s Work on this Topic

Error

Ethical Criteria for Self-Identifying Societal Risk Associated with Dangerous Gain-of-Function Research

A Roadmap for Accelerating Therapies for Parkinson's Disease

Advancing Development of LRRK2-Targeted Therapeutics for Parkinson’s Disease: Conference Proceedings and Roadmap for Research

Mapping the Informal Bioeconomy: Assessing the Current Landscape and Opportunities for Reinforcing Biosafety and Biosecurity

Toward Comprehensive Benchmarking of the Biological Knowledge of Frontier Large Language Models

Legitimate Research or Biological Threat? Detecting Misuse of the Biological Supply Network and Policy Options to Reduce Risks

A Review of U.S. Military Traumatic Brain Injury Studies: Trends, Gaps, and Opportunities

Experiential Learning from Rapid Evaluation in Health and Care

"Who Are You Going to Call?": Research Ethics Consultation Directors' Perspectives on Barriers and Facilitators

Defining Risk in Biological Research: Why Researchers Need Clearer Oversight Frameworks

Protecting Biological Materials and Services from Misuse: Opportunities for Access Monitoring and Control

When Should We Worry About AI Being Used to Design a Pathogen? Biology and AI Experts Weigh In

Oops! An unexpected error has occurred.